Tecosactide shine analog na corticotropin 24-peptide na roba.Jerin amino acid yayi kama da amino acid guda 24 na amino-terminal na corticotropin na halitta (mutum, bovine da porcine), kuma yana da aikin physiological iri ɗaya da ACTH na halitta."An kwatanta shi da rashin halayen antibody, gabaɗaya ba tare da mummunan tasiri ba, kuma ya dace musamman ga marasa lafiya waɗanda ke da halayen rashin lafiyan ko kuma ba su da tasiri ga corticotropin porcine na halitta."
"Yana haifar da hyperplasia na adrenal, yana motsa siginar hormones na adrenocortical, musamman (cortisol) da wasu mineralocorticoids irin su corticosterone, kuma yana motsa siginar androgens, amma tare da raunin rauni."
An sami ɗan tasiri akan ɓoyayyen aldosterone.Rabin rayuwar shine 3 hours.A cikin 2008, FDA ta amince da Tecokotide daga Novartis don ganewar rashin lafiyar adrenal.A halin yanzu ana nazarin shi a Jami'ar Randboud don kula da nephropathy na idiopathic membranous.
Duk hanyar haɗin lokaci na ruwa shine tsarin kira na ticacotide.Wannan hanya tana da matakai da yawa, tsawon lokaci mai tsawo, kuma yana buƙatar masu haɓaka masu tsada da kayan aiki masu mahimmanci, wanda ke da rashin amfani da tsada mai tsada, yawancin ƙazanta, haɗarin aiki, da ƙananan yawan amfanin ƙasa.An ba da rahoton cewa haɗakarwa ɗaya bayan ɗaya ta amfani da dabarun Z-kariya, wanda ake amfani da hydrogenation don cire tushen kariya a kowane mataki, yana da matakai masu tsayi, aiki mai wahala, tsada mai tsada da ƙarancin amfanin ƙasa.Serine yana da wuyar yin tseren tsere saboda haɗuwa ɗaya-da-daya yayin tsarkakewa, wanda ke da wuyar tsarkakewa.
"Kamar adrenocorticotropic hormone, ticcotide yana motsa siginar hormones na cortical (mafi yawan cortisol) daga cortex na adrenal."Sabili da haka, babu wani tasiri a cikin marasa lafiya tare da mummunan aiki na adrenocortical.
Ticocotide shine polypeptide na roba wanda ya ƙunshi amino acid 24.Daidai ne a cikin tsari da na farko zuwa amino acid na 24 na ACTH.Gudanar da jijiya cikin sauri yana ƙara matakan cortisol na jini.Ya kamata a yi amfani da ɗigon ɗigon jini mai ci gaba don kula da adadin cortisol na jini.Don allurar ciki, maganin cortisol ya kai kololuwar sa a sa'o'i 1 bayan allura.Bayan haka, ana iya kiyaye cortisol mai girma na kimanin sa'o'i 24.
Lokacin aikawa: Juni-28-2023