L-carnosine karamin kwayoyin halitta ne tare da tsarin dipeptide L-dipeptide na halitta wanda aka fi samuwa a cikin yanayi kuma ya ƙunshi nau'in dipeptide na L-dimbin halitta wanda aka saba samu a cikin yanayi.Dipeptide wanda ya ƙunshi β-alanine da L-histidine.Carnosine yana da nau'o'in antioxidant na salula, maganin tsufa da ayyukan kula da lafiyar jiki da kuma tasirin likita, irin su hauhawar jini, cututtukan zuciya, cataract na tsofaffi, farfadowa da ulcer, anti-tumor, gwajin samfurin rigakafi, abubuwan hana damuwa da sauransu.
Matsayin
Carnosine wani carnosine ne wanda masanin kimiyyar Rasha Gulevich ya samo tare da carnitine.A Birtaniya, Koriya, Rasha, da sauran Sin, bincike ya nuna cewa carnosine yana da karfin maganin antioxidant kuma yana da amfani ga mutane.An nuna Carnosine don cire nau'in oxygen mai amsawa (ROS) wanda aka kafa ta hanyar oxidation mai yawa na fatty acid a cikin kwayar halitta a lokacin damuwa na oxidative, da α-β unsaturated aldehydes.
Yawancin bincike sun gano cewa N-acetylcarnosine yana da tasiri mai kyau a cikin rigakafi da maganin cataract.Ɗaya daga cikin waɗannan binciken ya nuna cewa carnosine ya inganta cataracts wanda ke haifar da rashin daidaituwa na crystalline a cikin berayen da aka jawo ta hanyar fallasa ga guanidine.Ko da yake waɗannan ikirari suna goyan bayan fa'idodin ƙididdiga masu yawa ga ido kamar maganin carnotin don cataracts, har zuwa yau, ba su da cikakken goyon baya daga al'ummomin kiwon lafiya na yau da kullun.Masarautar Orthopedics, alal misali, sun yi iƙirarin cewa carnosine ba shi da aminci kuma ba shi da tasiri a cikin maganin cututtukan ido.
A cewar wani rahoto na 2002, carnosine na iya inganta zamantakewar zamantakewa da kuma ƙara ƙamus da yara masu autism ke amfani da su, amma ingantawar da aka yi da'awar a cikin binciken na iya fitowa daga ingantawa, placebo, ko wasu abubuwan da ba a rubuta a cikin wannan binciken ba.
Hanyar hadawa
A halin yanzu, hanyoyin samar da carnosine suna da wasu gazawa na yau da kullun: saboda iyakancewar halayen gefe, ana aiwatar da wannan gefen gefen tare da sa hannu na zoben L-histidine imidazole.L-histidine zai juya aƙalla 0.8% a cikin tsarin amsawa, rage yawan amfanin ƙasa;A lokaci guda, yana da wahala a raba L-carnosine tare da tsaftataccen tsaftataccen tsaftar ido daga gaurayawan cutarwa (yanayin juyawa, isomers imidazole, da sauransu), yana shafar tsabtar kasuwanci, saboda waɗannan gaurayawan suna da kaddarorin physicochemical iri ɗaya zuwa L-carnosine.Saboda kasancewar waɗannan gaurayawan, sakamakon L-carnosine yana da guba, maimakon ainihin shiri mai tsabta.
Sabuwar hanyar samar da L-carnosine kamar haka: phthalic anhydride yana amsawa β-alanine tare da phthalic anhydride β-phthaloylanine, chlorinated reagent chlorides phthaloyl-β-phthaloylalanine zuwa phthaloyl-alanine β-alanyl chloride;L-trialkylsilane mai kariya fili yana amsawa tare da trialkylchlorosilane ko hexahydroxysilane, yana amsawa tare da phthalyl β-alanyl chloride condensation na hydrochloride, yana kawar da rukunin karewa tare da barasa mai ban sha'awa, kuma yana haɓaka hydrochloride a cikin bayani na alkaline don samun samfurin tsaka-tsakin tsaka-tsaki, hydrazine premisalihydrate hydrochloride, hydrazine. L-carnosine a cikin barasa anhydrous.Wannan samfurin zoben imidazole ne akan histidine mai kariya na L don kauce wa illar zoben imidazole akan L-histidine da sauran abubuwa, da samun L-carnosine mai tsabta tare da ƙananan sakamako masu illa da yawan yawan amfanin ƙasa da abun ciki.
Lokacin aikawa: Oktoba-24-2023