Yayin da ake kira peptide, ana buƙatar ƙara wasu gishiri.Amma akwai nau'ikan gishiri iri-iri, kuma nau'ikan gishiri daban-daban suna yin peptides daban-daban, kuma tasirin ba iri ɗaya bane.Don haka a yau mun fi zaɓar nau'in gishirin peptide da ya dace a cikin haɗin peptide.
1. Trifluoroacetate (TFA): Wannan gishiri ne da aka saba amfani dashi a cikin kayayyakin peptide, amma yana buƙatar kaucewa a wasu gwaje-gwajen saboda biotoxicity na trifluoroacetate.Misali, gwajin kwayar halitta.
2. Acetate (AC): Halin halittu na acetic acid ya fi ƙasa da trifluoroacetic acid, don haka yawancin magunguna da peptides na kwaskwarima suna amfani da acetate, amma wasu samfurori suna da acetate maras kyau, don haka kwanciyar hankali na jerin kuma yana buƙatar la'akari.An zaɓi acetate don yawancin gwaje-gwajen tantanin halitta.
3. Hydrochloric acid (HCL): Wannan gishiri ba kasafai ake zabar shi ba, kuma wasu jeri ne kawai suke amfani da acid hydrochloric don dalilai na musamman.
4. Gishirin Ammonium (NH4 +): Wannan gishiri zai yi tasiri sosai ga solubility da kwanciyar hankali na samfurin, dole ne a zaba domin.
5. Gishirin sodium (NA +): gabaɗaya yana shafar kwanciyar hankali da narkewar samfur.
6. Pamoicacid: Ana yawan amfani da wannan gishiri a cikin magungunan peptide don yin abubuwan sakewa mai dorewa.
7. CitricAcid: Wannan gishiri yana da ɗan ƙaramin guba na physiological, amma shirye-shiryensa yana da rikitarwa sosai, don haka tsarin samarwa yana buƙatar haɓakawa bi da bi kuma daban.
8. Salicylicacid: Salicylate zai iya rinjayar zaman lafiyar samfurori na peptide, don haka da wuya a yi amfani da shi.
Abubuwan da ke sama sune nau'ikan gishirin peptide da yawa, kuma yakamata mu zaɓi bisa ga halayen gishiri daban-daban a ainihin amfani.
Lokacin aikawa: Juni-16-2023