Peptide na al'ada

Peptide na al'adaMaganaSabis

Hangzhou Go Top Peptide Biotech , wanda aka kafa a cikin 2014, shine a National High-tech Enterpriseƙware a cikin bincike, haɓakawa da samar da peptides da abubuwan da suka dace.

Kamfaninpeptide bincike cibiyarA halin yanzu yana cikin gundumar Qiantangof Hangzhou, wanda ke da fadin fiye da murabba'in mita 3,000.Thekamfani's factory yana a No.24, Hanyar Haiti, gundumar Shangyu, birnin Shaoxing, lardin Zhejiang.Akwai kuma biyu hadin gwiwa shuke-shuke, daya donkasuwanci peptide GMP masana'antu dake cikinAnji lardin Zhejiang, ɗaya don ƙananan kwayoyin API da ke cikinBirnin Yuncheng na lardin Shanxi.Mun zamawani m high-tech sha'anin, Haɗa bincike, ƙaddamar da matukin jirgi, kasuwanci da tallace-tallace na duniya.

Kamfanin yana daa kan100ma'aikata,kuma yana daci gaba fiye da40 balagagge Pharmaceuticalpeptides,fiye da10 ƙirƙira haƙƙin mallakaan ba da izini.Tya shekara-shekara samar iya aikiis har zuwakilogiram 100, adadin peptides na al'ada yana da ya kai sama da 20,000.Za mu iya ba da sabis na peptide na tsayawa ɗaya daga bincike (mg) zuwa kasuwanci (KGs).

Jerin Gyaran Peptide

N-gyare-gyaren tasha

{N-Me-Ala} {N-Me-Asp} {N-Me-Glu} {N-Me-Ile}
{N-Me-Leu} {N-Me-Met} {N-Me-Nle} {N-Me-Nva}
{N-Me-Phe} {N-Me-Ser} {N-Me-Thr} {N-Me-Tyr}
{N-Me-Val} {Sar} N-Me-Arg N-Me-Asn
N-Me-beta-Ala N-Me-Gln N-Me-Lys N-Me-Trp

C-gyare-gyaren tasha

{Mono Disulfide gada} {Gadar Disulfide Biyu} {Triple Disulfide gada}
{Random Disulfide gada} {Sai Seq.Inter-Disulfide gada } {Gadar Inter-Disulfide daban-daban}
{Amide cyclic (ƙarshen)} {Amide cyclic (Side sarkar)} { sarkar gefe Amide cyclic}
{Thoester cyclic} {lactone cyclic} {Siki na biyu}

Amino acid da ba a saba ba

{2-Aze} {3-Aze} {5,5-Dime-Pro}
{5-ASA} {Abu} {Ac-Lys}
{Abin} {Beta-Asp} {Bpa}
{Cha} {Chg} {Cit}
{Cpg} {Cys(Acm)} {Cys(Bzl)}

Isotope mai lakabin peptides

Lys (13C6,15N2) Ile(13C6,15N)
Leu (13C6,15N) Val (13C5, 15N)
Arg (13C6, 15N4)  

 Fluorescent peptide gyare-gyare / FRET nau'i-nau'i

Biotin- Dansyl- Quenched peptide fluorecent
Biotin-Ahx- Dansyl-Ahx- Dabcyl
5-FAM- Cy3- Dabcyl / Glu(Edans) -NH2
5-FAM-Ahx- Cy5- Dansyl-
FITC- MCA/DNP Dansyl-Ahx-
FITC-Ahx- AMC Edans / Dabcyl

Peptide Conjugates

BSA (-COOH na tashar C KLH(-NH2 na tashar N) OVA (-COOH na tashar C)
Haɗin BSA akan Cys KLH Conjugation akan Cys OVA(-NH2 na tashar N)
    Haɗin OVA akan Cys

 Phosphorylation

{pSer} {D-pSer}
{pTyr} {D-pTyr}
{pThr} {D-pThr}

Sauran gyare-gyare (PEGylation, gyare-gyare na cyclic, gada na Disulfide)

PEGylation gyare-gyare na cyclic Disulfide Bridges
{Mini-PEG1} Yi tafiya zuwa wutsiya {Mono Disulfide gada}
{Mini-PEG2}   {Gadar Disulfide Biyu}
{PEG-11}   {Triple Disulfide gada}
{PEG-12}   {Random Disulfide gada}
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